https://www.wagnerkapoor.com/contents/clinical-trials/active-studies
"Study: MK-8748-006 RVO
Age: greater than or equal to 18 years of age
Presence of ME-RVO: CST ≥325 μm in the study eye on spectral-domain optical coherence tomography (SD-OCT)
Treatment-naïve (diagnosed within the last 4 months)
Best-Corrected Visual Acuity (BCVA) Early Treatment of Diabetic Retinopathy Study (ETDRS) between 73 and 19 (20/40 to 20/400 Snellen)
Decrease of BCVA must be primarily the result of ME-RVO
About this Study:
A Randomized, Double-Masked, Multicenter, 3 Arm, Pivotal Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal (IVT) MK-8748 Compared With Aflibercept (2 mg) in Participants with Macular Edema Following Retinal Vein Occlusion (ME-RVO)
"
https://retinacentertx.com/research/clinical-trials
Clinical Trials | Retina Center of Texas
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미국 임상기관중 여러곳을 보면..
BRVO 3상, MK-8748-006의 임상이 보인다..
아마 선행 등록 된것으로 보이는데..
(추측컨데 현재 IND신청 진행중이지 않을까 생각해본다.)
곧, clinical trial에도 정식 등록 되지 않을까 생각해본다.
" - MK-8748 저용량 Vs MK-8748 고용량 Vs 아일리아 2mg "
또한, 빠른(?) 상업화 전략상 BRVO - 2개의 임상을 동시에 진행하지 않을까 추측도 가능하다.. (2번째 임상은 MK-8748-007 이겠지!!)